The plot of The Witcher 2 is intended to be less linear than that of the first game, and is supposed to feature "three independent plot lines" which lead to multiple endings.
The Witcher 2 is set almost immediately after the first, and follows from the attempt on King Foltest's life which occurred in the final cutscene. Geralt will once again face the mysterious witcher-like assassins, who appear to be connected with a character named in previews as the Kingslayer. In a trailer, the Kingslayer is seen speaking to Iorveth, a human-hating elf. The Kingslayer displays a head which he claims belonged to King Demawend of Aedirn, and says that if Iorveth is prepared to help, more kings will also fall.
Other plot elements which have been referenced (but which do not necessarily correspond to the three plot lines mentioned) are Foltest's moves to capture the stronghold of the rebellious Baroness La Valette and "Geralt’s personal theme, in which he’s looking for his own identity".
According to a fact sheet released for the game, Geralt's travels "will lead him up the river Pontar into the turbulent borderland between Temeria, Kaedwen and Aedirn". A town named Flotsam, situated on the border between Temeria and Aedirn, will feature.
Characters returning from the first game include Triss Merigold, Zoltan, and Dandelion. A new character to be introduced is Vernon Roche, a member of the Temerian military who has been sent to help Geralt.
Though it is not not known where in the narrative it will take place (if at all) it may be speculated that Geralt will face off against a dragon. (may be speculated from the original, leaked, gameplay trailer from September '09 which shows a dragon along with another of the mysterious assassins). Also a concept piece shows what looks like some form of dragon in the background of it, the only living thing in view. (to the right hand side)