At the end of this mission, you can choose between two Twists of Fate
To destroy the pillars, you need to equip the Mystic Hammer.
When you are given the "Make me your instrument/That will never happen" choice, if you choose thumbs up, you unlock the Khamazandu's Gift quest.
The prison of Niskaru Lord Khamazandu is in the Cloudcrest Mountain, on the southern edge of the Hollowlands. This is where Anru Besin will be and where I must go.
Twist of Fate - Truesworn: +1 to Might Abilities, +10% Chance to Critical Hit vs. Niskaru, +6% Stun Duration.