The game sees players in the role of Scrooge McDuck as he travels across the world in search of five treasures to further increase his fortune.
Many of the original game's levels are featured, along with new areas added for the remake and new boss patterns.The game features new story elements which explain some of the motives and reasoning behind each level, such as how Scrooge is able to breathe on the Moon. The game also features almost identical gameplay of the original, with a few gameplay tweaks, such as a map screen and an easier pogo jump, which can be toggled on and off. DuckTales: Remastered features a new tutorial level, set in Scrooge's money vault, and a new level leading up to the final boss. Money gathered in levels can now be used to unlock various gallery items such as concept art and pieces of music.